Abstract Bacteria-mediated cancer therapeutic strategies have attracted increasing interest due to their intrinsic tumor tropism.However, bacteria-based drugs face several challenges including Hot Deals the large size of bacteria and dense extracellular matrix, limiting their intratumoral delivery efficiency.In this study, we find that hyperbaric o
The seminal description of the cellular restriction factor APOBEC3G and its antagonism by HIV-1 Vif has underpinned two decades of research on the host-virus interaction.We recently reported that HIV-1 Vif is also able to degrade the PPP2R5 family of regulatory subunits of key cellular phosphatase PP2A (PPP2R5A-E; Greenwood et al., 2016; Naamati et
The results of experimental research involving nine one-way slabs are detailed in this report.The Honey objective was to investigate the impact of different parameters on the structural performance of these slabs in their absence and with strengthening.Externally bonded CFRP sheets strengthened six of the nine slabs; the three remaining slabs serve
Summary: Southeast Asia has been the hotbed for the development of drug-resistant malaria parasites, including those with resistance to artemisinin combination therapy.While mutations in the kelch propeller domain (K13 mutations) are associated with artemisinin resistance, a range of evidence suggests that other factors are critical for the establi
Adopting standalone indicators to characterise landscape composition is vital because it allows for targeted assessments without surveying entire communities.We hypothesised that barbastelle bat (Barbastella barbastellus) presence would provide sufficient indication power to characterise forest landscapes in Italy and employed logistic regression t